In the region, more than two million adults, youth and children live with HIV. Every two minutes a person gets infected, and 300 people die every day through AIDS-related causes. The Caribbean has the second highest HIV rate in the world, after Sub-Saharan Africa.

Haiti, the Dominican Republic, Honduras and Guatemala, among other countries, have generalized epidemics with HIV rates above one percent of the general population. Haiti, with a 3.8 percent rate, is the most affected country in the Caribbean. Brazil hosts more than a third of the total infected people in Latin America.

While in several countries the epidemic has remained focused on vulnerable populations that are exposed to higher risk, there is an increasing tendency to new infections among women in the general population.

In order to reduce the incidence of HIV and improve the quality of life of affected children, families and communities, World Vision’s "Hope Initiative Against HIV and AIDS" strategically focuses its efforts on educating children and adolescents and empowering women to diminish their greater vulnerability, addressing higher-risk vulnerable groups, advocating for holistic care of people living with HIV/AIDS, and working in strategic alliances.